Prescribe Right
Prescribe Right
  • Home
  • About
    • Endorsements
    • Published Articles
    • Consulting
    • Effective Pharmacotherapy
  • Pipeline News
    • Podcast
    • Recent Tweets
  • Pharmaceutical Pipeline Tracker
    • Access Pharmaceutical Pipeline Tracker
    • Pharmaceutical Pipeline Tracker Demo
    • Sample Drug Review
    • Case Studies >
      • Monitoring Drugs With PDUFA Dates
      • Monitoring Drugs By Therapeutic Category
      • Monitoring by Indication
      • Research a Single Drug
    • Sample Searches >
      • Single Drug Report Sample
      • Indication Search Sample
      • Drug Class Search Sample
      • Therapeutic Area Search Sample
      • Company Search Sample
  • Contact Us
  • Home
  • About
    • Endorsements
    • Published Articles
    • Consulting
    • Effective Pharmacotherapy
  • Pipeline News
    • Podcast
    • Recent Tweets
  • Pharmaceutical Pipeline Tracker
    • Access Pharmaceutical Pipeline Tracker
    • Pharmaceutical Pipeline Tracker Demo
    • Sample Drug Review
    • Case Studies >
      • Monitoring Drugs With PDUFA Dates
      • Monitoring Drugs By Therapeutic Category
      • Monitoring by Indication
      • Research a Single Drug
    • Sample Searches >
      • Single Drug Report Sample
      • Indication Search Sample
      • Drug Class Search Sample
      • Therapeutic Area Search Sample
      • Company Search Sample
  • Contact Us
Pipeline News and Updates
Picture

Update for July 19, 2022

7/19/2022

 
Regulatory Update
 
The FDA delayed a decision for tislelizumab, until a site inspection of BeiGene’s Chinese manufacturing facility can be completed. Travel issues related to COVID-19 have prevented the FDA from inspecting the plant. 
 
Announced Research Updates
 
Pluristem announced that in a 26-week, 240 patient, Phase III trial, treatment with PLX-PAD did not improve the Short Physical Performance Battery (SPPB) test score compared to placebo in patients undergoing hip arthroplasty following fracture. 
 
Sesen Bio voluntarily paused development of oportuzumab monatox and is seeking financial partners to help fund further development.
 
Published Research Updates
 
In the 16-week, 666 patient, Phase III, POETYK PSO-1 trial, 58.4% of patients treated with deucravacitinib achieved PASI 75 and 53.6% achieved a Physician's Global Assessment (sPGA) score of 0 to 1 compared to 35.1% and 32.1% with apremilast and 12.7% and 7.2% with placebo in patients with moderate to severe psoriasis. 
 
In the 112 patient cohorts of the Phase II, KRYSTAL-1 trial, treatment with adagrasib resulted in an ORR of 42.9% in patients with non-small cell lung cancer (NSCLC) harboring the KRAS G12C mutation, who had been treated with platinum-based chemotherapy and anti-programmed death 1 or programmed death ligand 1 therapy.
 
In a 100 patient, Phase 1b trial, treatment with zandelisib resulted in an objective responses of 92% with 60 mg and 120 mg, and 83% with 180 mg in patients with relapsed or refractory B-cell malignancy.
 
In the 20-week, 139 patient, Phase II ELEKTRA trial, treatment with soticlestat resulted in a 50% reduction in convulsive and drop seizure frequencies in Dravet syndrome patients compared to placebo. The decrease in seizures in Lennox-Gastaut syndrome patients was not significantly better than placebo.


Comments are closed.
    Stay informed, subscribe to the 
    ​
    Prescribe Right Pharmaceutical Pipeline Tracker
    Latest Tweets from Prescribe Right

    Archives

    March 2023
    February 2023
    January 2023
    December 2022
    October 2022
    September 2022
    August 2022
    July 2022
    June 2022
    May 2022
    April 2022
    March 2022
    February 2022
    January 2022
    December 2021
    November 2021
    October 2021
    September 2021
    August 2021
    July 2021
    June 2021
    May 2021
    April 2021
    March 2021
    February 2021
    January 2021
    December 2020
    November 2020
    October 2020
    September 2020
    August 2020
    July 2020
    June 2020
    May 2020
    April 2020
    March 2020
    February 2020
    January 2020
    December 2019
    November 2019
    October 2019
    September 2019
    August 2019
    July 2019
    June 2019
    May 2019
    April 2019
    March 2019
    February 2019
    January 2019
    December 2018
    November 2018
    October 2018
    September 2018
    August 2018
    June 2018
    May 2018
    April 2018
    March 2018
    February 2018
    January 2018
    December 2017
    November 2017
    October 2017
    September 2017
    August 2017
    August 2015

    RSS Feed

Services

Pharmaceutical Pipeline Tracker​
Consulting

Company

About
Blog
Tweets

Support

Contact
© COPYRIGHT 2015. ALL RIGHTS RESERVED.