Prescribe Right
Prescribe Right
  • Home
  • About
    • Endorsements
    • Published Articles
    • Consulting
    • Effective Pharmacotherapy
  • Pipeline News
    • Podcast
    • Recent Tweets
  • Pharmaceutical Pipeline Tracker
    • Access Pharmaceutical Pipeline Tracker
    • Pharmaceutical Pipeline Tracker Demo
    • Sample Drug Review
    • Case Studies >
      • Monitoring Drugs With PDUFA Dates
      • Monitoring Drugs By Therapeutic Category
      • Monitoring by Indication
      • Research a Single Drug
    • Sample Searches >
      • Single Drug Report Sample
      • Indication Search Sample
      • Drug Class Search Sample
      • Therapeutic Area Search Sample
      • Company Search Sample
  • COVID-19
    • COVID-19 Updates
    • COVID-19 Vaccines
    • COVID-19 Antivirals
    • COVID-19 Monoclonal Antibodies
    • COVID-19 Plasma Products
    • COVID-19 Anti-Inflammatories
    • Remdesivir
    • Ivermectin
  • Contact Us
  • Home
  • About
    • Endorsements
    • Published Articles
    • Consulting
    • Effective Pharmacotherapy
  • Pipeline News
    • Podcast
    • Recent Tweets
  • Pharmaceutical Pipeline Tracker
    • Access Pharmaceutical Pipeline Tracker
    • Pharmaceutical Pipeline Tracker Demo
    • Sample Drug Review
    • Case Studies >
      • Monitoring Drugs With PDUFA Dates
      • Monitoring Drugs By Therapeutic Category
      • Monitoring by Indication
      • Research a Single Drug
    • Sample Searches >
      • Single Drug Report Sample
      • Indication Search Sample
      • Drug Class Search Sample
      • Therapeutic Area Search Sample
      • Company Search Sample
  • COVID-19
    • COVID-19 Updates
    • COVID-19 Vaccines
    • COVID-19 Antivirals
    • COVID-19 Monoclonal Antibodies
    • COVID-19 Plasma Products
    • COVID-19 Anti-Inflammatories
    • Remdesivir
    • Ivermectin
  • Contact Us
Pipeline News and Updates
Picture

Focus on Investigational Drugs to Treat Heart Failure

10/17/2019

 
We have been focusing on Cancer with our last updates focused on Breast Cancer and Lung Cancer.

We take a moment now to focus on the number one cause of death in the US, Heart Disease.

There are eleven investigational drugs for Heart failure in the Pharmaceutical Pipeline Tracker. Of the 23 investigational drugs with PDUFA dates, none are targeting Heart Failure. However, three investigational drugs to treat Heart failure have FDA Priority Designations.

​Vericel’s ixmyelocel-T is a fully closed cell-processing system that expands mesenchymal stromal cells and macrophages, which create anti-inflammatory and pro-angiogenic factors to repair damaged tissue and is administered via transendocardial injection.  Ixmyelocel-T has orphan drug status for dilated cardiomyopathy and Fast Track status for peripheral ischemia.  It has also received a Regenerative Medicine Advanced Therapy (RMAT) designation from the FDA along with a Rare Pediatric Disease designation. There are links to two published studies for Ixmyelocel-T in the Pharmaceutical Pipeline Tracker.

Mesoblast’s MPC-150-IM is a mesenchymal precursor cell therapy that is administered via Intravenous Infusion in Phase III trials. MPC-150-IM is competing with Biocardia's autologous mesenchymal stem cell product. Mesoblast has the ongoing 600 patient, Phase III, DREAM HF-1 trial evaluating whether MPC-150-IM can reduce nonfatal heart failure-related major adverse cardiac events in moderate heart failure patients. The FDA has given MPC-150-IM a Rare Pediatric Disease and Regenerative Medicine Advanced Therapy (RMAT) priority designations. There is one published study for MPC-150-IM in the Pharmaceutical Pipeline Tracker.

Ironwood Pharmaceuticals’ praliciguat is an oral soluble guanylate cyclase (sGC) stimulator that improves nitric oxide (NO) signaling, which is being developed for heart failure with preserved ejection fraction (HFpEF) and diabetic nephropathy. The drug is in an on-going Phase II Trial and has a Fast Track priority designation from the FDA.

Subscribe to the Pharmaceutical Pipeline Tracker to review investigational drugs focused on Heart Failure. Read about safety, efficacy and the latest news. Take a look at published research links.


Comments are closed.
    Stay informed, subscribe to the 
    ​
    Prescribe Right Pharmaceutical Pipeline Tracker
    Latest Tweets from Prescribe Right

    Archives

    January 2023
    December 2022
    October 2022
    September 2022
    August 2022
    July 2022
    June 2022
    May 2022
    April 2022
    March 2022
    February 2022
    January 2022
    December 2021
    November 2021
    October 2021
    September 2021
    August 2021
    July 2021
    June 2021
    May 2021
    April 2021
    March 2021
    February 2021
    January 2021
    December 2020
    November 2020
    October 2020
    September 2020
    August 2020
    July 2020
    June 2020
    May 2020
    April 2020
    March 2020
    February 2020
    January 2020
    December 2019
    November 2019
    October 2019
    September 2019
    August 2019
    July 2019
    June 2019
    May 2019
    April 2019
    March 2019
    February 2019
    January 2019
    December 2018
    November 2018
    October 2018
    September 2018
    August 2018
    June 2018
    May 2018
    April 2018
    March 2018
    February 2018
    January 2018
    December 2017
    November 2017
    October 2017
    September 2017
    August 2017
    August 2015

    RSS Feed

Services

Pharmaceutical Pipeline Tracker​
Consulting

Company

About
Blog
Tweets

Support

Contact
© COPYRIGHT 2015. ALL RIGHTS RESERVED.