COVID-19 Vaccines
Sinopharm has priced its COVID-19 vaccine at $145 for two doses. COVID-19 Antibodies Regeneron has signed an agreement with Roche to increase manufacturing capacity and distribution of REGN-COV2, Regeneron’s mixture of two monoclonal COVID-19 antibodies. Roche will triple the manufacturing capacity for REGN-COV2 and handle distribution outside the U.S. Aviptadil Aviptadil (RLF-100) is a synthetic human Vasoactive Intestinal Polypeptide. Aviptadil blocks the replication of the SARS coronavirus in human lung cells and monocytes. The drug has been in clinical trials since 2001 and was unsuccessfully evaluated for Acute Respiratory Distress Syndrome and Pulmonary Arterial Hypertension.
Tradipitant is a neurokinin-1 receptor (NK-1R) antagonist being developed by Vanda Pharmaceuticals for the treatment of diabetic gastroparesis, motion sickness, and atopic dermatitis. By inhibiting NK-1R, tradipitant is thought to decrease inflammatory lung injury associated with severe or critical COVID-19 pneumonia.
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